Manifestations of Brucellosis: A Systematic Review

  • S. N. Ghodasara Cattle Breeding Farm, Junagadh Agricultural University, Junagadh, Gujarat- 362 001
  • H. H. Savsani Department of Animal Nutrition,2Department of Veterinary Pathology, College of Veterinary Science & A. H., Junagadh Agricultural University, Junagadh, Gujarat – 362 001
  • V. A. Kalaria Department of Animal Nutrition,2Department of Veterinary Pathology, College of Veterinary Science & A. H., Junagadh Agricultural University, Junagadh, Gujarat – 362 001
  • A. R. Bhadaniya Cattle Breeding Farm, Junagadh Agricultural University, Junagadh, Gujarat- 362 001
Keywords: Abortion, Infertility, Livestock, Zoonosis

Abstract

Brucellosis is a major bacterial zoonosis of global importance. The causative organism is Gram-negative facultative intracellular pathogens that may affect a range of different mammals including man, cattle, sheep, goats, swine, rodents and marine mammals. Brucellosis is caused by different species of Brucella and is cause significant economically losses to livestock industries. The disease is manifested by reproductive disorder, viz., infertility, retained placenta, abortions and endometritis in livestock species, hence it leads to loss in productivity of animals and consequently to economic losses. Despite the advances made in the diagnosis and therapy, brucellosis is still wide spread and its prevalence in many developing countries is increasing.

References

1. Alton, G.; Jones, L. M.; Angus, R. D. and Verger, J. M. (1988). Techniques for the Brucellosis Laboratory. INRA, Paris.
2. Banai, M., Mayer, I. and Cohen, A. (1990). Isolation, Identification, and Characterization in Israel of Brucella melitensis Biovar 1 Atypical Strains Susceptible to Dyes and Penicillin, Indicating the Evolution of a New Variant. Journal Of Clinical Microbiology 28:1057-1059
3. Bendixen, H.C. and E. Blom. 1947. Investigations on Brucellosis in the bovine male, with special regard to spread of the disease by artificial insemination. Vet J. 103:337-345.
4. Bikas, C., Jelastopulu. E., Leotsinidis, M. and Kondakis, X. (2003). Epidemiology of human brucellosis in a rural area of northwestern Peloponnese in Greece. Eur J Epidemiology. 18 : 267-74.
5. Blasco, J.M., Marin, C., Jimenez de Bagues, M.P. and Barberan, M. (1993). Efficacy of Brucella suis strain 2 vaccine against Brucella ovis in rams. Vaccine. 11:1291-1294.
6. Blood, D. C., Radostits, O. M., Henderson, J. A., Arundel, J. H. and Gay, C. C. (1983). Veterinary Medicine- A Textbook of the Diseases of Cattle, Sheep, Pigs, Goats and Horse. Sixth Edition.
7. Bricker, B. J. and Halling, S. M. (1994). Differentiation of Brucella abortus bv. 1, 2 and 4, Brucella melitensis, Brucella ovis and Brucella suis bv 1 by PCR. J. Clin. Microbiol. 32: 2660-2666.
8. Bricker, B.J., Ewalt, D.R., MacMillan, A.P., Foster, G. and Brew, S. (2000). Molecular characterization of Brucella strains isolated from marine mammals. J. Clin Microbiol. 38:1258-62.
9. Camus, (1980). Incidence clinique de la brucellose bovine dans le nord de la Côte-d’Ivoire. Rev. Elev. Méd. vét. Pays trop., 33 (3): 263-269 (in French).
10. Chand, P. and Sharma, A. K. (2004). Situation of brucellosis in bovines at organized cattle farms belonging to three different states. Journal of Immunology & amp. Immunopathology. 6:11-15.
11. Chand, P.; Sadana, J. R.; Batra, H. V. and Chauhan, R. S. (1989). Comparison of Dot Immunobinding Assay with complement fixation test for the detection of brucella antibodies in sheep. Vet. Microbiology. 20:281-287.
12. Chatterjee, A.; De, B. N.; Mondal, P.; Bidyanta, J.; Chakraborty, M. K.; Nandy, A. K. and Sen, G. P. (1986). Studies on seroprevalence of bovine brucellosis in rural West Bengal. Indian Vet. J. 63: 95-100
13. Chukwu, C.C. (1987). Brucellosis in Africa. Part II: The importance Bull. Anim. Hlth. Prod. Afr.35: 92-98.
14. Corbel, M. J. (1972). Characterization of antibodies active in the Rose Bengal Plate Test for bovine brucellosis. Vet. Rec. 88: 447-449.
15. Corbel, M. J. (1988). Brucellosis. In: Fertility and Infertility in Veterinary Practice. pp. 189-221. Laing, J. A. (ed), 4th Edition. ELBS, Bailliere Tindall.
16. Corbel, M.J. (1997): Brucellosis: an overview. Emerg Infect Dis. 3 : 213-21.
17. Corbel, M.J. and Morgan, W.J.B. (1984). Genus Brucella. Meyer and Shaw. In: Kreig, N.R., Holt, J.G. (Eds.), Bergey’s Manual of Systematic Bacteriology, Williams and Wilkins, Baltimore, pp.377–388.
18. Cutler, S. J., Whatmore, A.M. and Commander N.J. (2005). Brucellosis – new aspects of an old disease. J. of Applied Microbiology. 98: 1270–1281.
19. Elberg, S. (1996). Rev.1 Brucella melitensis vaccine. Part III 1981-1995. Veterinary Bulletin. 66: 1193-1200.
20. Ergonul, O., Willke, A., Azap, A. and Tekeli, E. (2005). Revised definition of ‘fever of unknown origin’: limitations and opportunities. J. Infect. 50 : 1-5.
21. Gallien, P., Dorn, C., Alban, G., Staak, C. and Protz, D. (1998). Detection of Brucella species in organs of naturally infected cattle by polymerase chain reaction. Vet. Rec. 142: 512-514.
22. Giannacopoulos, I., Eliopoulou, M.I., Ziambaras, T. and Papanastasiou, D.A. (2002). Transplacentally transmitted congenital brucellosis due to Brucella abortus. J. Infect. 45: 209-10.
23. Groussaud, P., Shankster, S. J., Koylass, M. S. and Whatmore, A. M. (2007). Molecular typing divides marine mammals strains of Brucella into at least three groups with distinct host preference. J. Med. Microbiology. 56: 1512-1518.
24. Guarino, A.; Serpe, L.; Fusco.; Scaramuzzo, A. and Gallo, P. (2000). Detection of Brucella spp in Buffalo whole blood by gene-specific PCR. Vet. Record. 147: 634-636
25. Gur, A., Geyik, M.F., Dikici, B., Nas, K., Cevik, R., Sarac, J. (2003) .Complications of brucellosis in different age groups: a study of 283 cases in southeastern Anatolia of Turkey. Yonsei Med. J. 4: 33-44.
26. Holger C. S. et al. (2008). Brucella microti sp. nov., isolated from the common vole Microtus arvalis. Int J Syst Evol Microbiol. 58:375-382
27. Jahans, K. L., G. Foster, and E. S. Broughton. 1997. The characterisation of Brucella strains isolated from marine mammals. Vet. Microbiol. 57:373-382
28. Jeyaprakash, C.; Ranjitsingh, A. J. A. and Amuthan, A. (1999). Isolation of Brucella spp. from indigenous and cross-bred cows and evaluation of their antibiogram. Indian J. Anim. Res. 33: 99-103.
29. Johnson, C.A. and Walker, R.D. (1992). Clinical signs and diagnosis of Brucellacanis infection. The Comp Cont Educ. 14:763–72.
30. Kanani, A. N. (2007). Serological, cultural and molecular detection of Brucella infection in breeding bulls. A thesis submitted to A. A. U., Anand.
31. Kocak, I., Dundar, M., Culhaci, N. and Unsal, A. (2004). Relapse of brucellosis simulating testis tumor. Int. J. Urol. 11.
32. Kochar, D.K., Kumawat, B.L., Agarwal, N., Shubharakaran, N., Aseri, S. and Sharma, B.V. (2000). Meningoencephalitis in brucellosis.Neurol. India. 48 : 170-3.
33. Lubbehusin, R.E. and C.P. Fitch. (1926). A report of experimental work on the bull as a factor in the spread of infectious abortion, J. Am. Vet. Med. Assoc. 69+467481.
34. Mahato, G.; Sharma, K. and Mahanta, P. N. (2004). Comparative evaluation of serological tests for detection of Brucellosis in bovine. Indian J. Vet. Med. 24: 46.
35. Manterola, L., Tejero Garces, A., Ficapal, A., Shopayeva, G., Blasco, J. M., Marin, C. M. and Lopez Goni, I. (2003). Evaluation of a PCR test for the diagnosis of Brucella ovis infection in semen samples from rams. Vet. Microbiol. 92: 65-72.
36. Manthei, C.A., D.E. Detray and E.R. Goode. 1950. Brucella infection in bulls and the spread of brucellosis in cattle by artificial insemination. Proc. Am. Vet. Med. Assoc. 87th Ann. Meet., 177-184.
37. McDermott, J.J., Deng, K.A., Jayatileka, T.N. and Jack, M.A. (1987). A Cross-sectional Cattle Disease Study in Kongor Rural Council, Southern Sudan. II. Brucellosis in Cows: Associated Factors, Impact on Production and Disease Control Considerations. Prev. Vet. Med. 5: 125-132.
38. Mcmahan, V. K. (1944). Brucellosis of cattle. Circular–222. Kansas Agricultural Experiment Station, Kansas State College of Agricultural and Applied Science. Manhattan, Kansas, USA.
39. Mehra, K. N., Dhanesar, N. S., Chaturvedi, V. K. (2000). Sero-prevalence of brucellosis in bovines of Madhya Pradesh. Indian Vet. J. 77: 571-573.
40. Mesner, O., Klaris Riesenberg, Natalia Biliar, Eliezer Borstein, Leah Bouhnik, Nehama Peled, and Pablo Yagupsky (2007). The Many Faces of Human-to-Human Transmission of Brucellosis: Congenital Infection and Outbreak of Nosocomial Disease Related to an Unrecognized Clinical Case. CID. 45: 135-140.
41. Nicoletti, P. (1990).Vaccination. In: Nielsen K and Duncan JR eds., Animal brucellosis. CRC Press, Inc., Boca Raton, Fla. 283-299.
42. Nuru, S. and Schnurrenberger, P., (1975). The present status of Bovine Brucellosis in Nigeria: Its prevalence, significance and areas of research need. Bull. Offi. Int. Epiz. 83: 1113- 1123.
43. Omer, M.K., Assefaw, T., Skjerve, E., Tekleghiorghis, T. and Woldehiwet, Z. (2002). Prevalence of antibodies to Brucella spp.and risk factors related to high-risk occupational groups in Eritrea. Epidemiol. Infect. 129: 85-91.
44. Palanduz, A., Palanduz, S., Guler, K. and Guler, N. (2000). Brucellosis in a mother and her young infant: probable transmission by breast milk. Int. J. Infect. Dis. 4: 55-6.
45. Probert, W. S., Schrader, K. N., Khuong, N. Y., Bystrom, S. L. and Graves, M. H. (2004). Real-time Multiplex PCR Assay for Detection of Brucella spp., B. abortus, and B. melitensis. J. Clin. Microbiol. 42: 1290–1293.
46. Rankin, J.E.F. 1965. Brucella abortus in bulls: A study of twelve naturally-infected cases. Vet. Rec. 77:132-135.
47. Refai, M. (2002). Incidence and control of brucellosis in the Near East region. Vet. Microbiology. 90: 81-110.
48. Renukaradhya, G. J., Isloor, S. and Rajasekhar, M. (2002). Epidemiology, zoonotic aspects, vaccination and control/eradication of brucellosis in India. Vet. Microbiol. 90: 183-195.
49. Richtzenhain, L. J., Cortez, A., Heinemann, M. B., Soares, R. M., Sakamoto, S. M., Vasconcellos, S. A., Higa, Z. M. M., Scarcelli, E. and Genovez, M. (2002). A multiplex PCR for the detection of Brucella spp. and Leptospira spp. DNA from aborted bovine fetuses.Vet. Microb. 87: 139–147.
50. Robert, L. J.; Billy, L. D.; Margaret, E. M.; Gerald, M. B. and William, H. F. (1982). Iolation of two Brucella abortus biotypes from tissues of a naturally infected cow. J. of Clin. Microb. 16: 641-643.
51. Sarumathi, C.; Reddy, T. V.; Sreedevi, B. and Rao, U. V. N. M. (2003). Comparison of avidin-biotin ELISA with RBPT and STAT for screening of antibodies to bovine brucellosis. Indian Vet. Journal 80: 1106-1108.
52. Stoenner, H.G. and Lackman, D. B. (1957). A new species of Brucella isolated from the desert wood rat, Neotoma lepida Thomas. Am. J. Vet. Res. 18:947–951.
53. Verger, J. M., Grimont, F., Grimont, P. D. A. and Grayon, M. (1985). Brucella, a monospecific genus as shown by deoxyribonucleic acid hybridization. Int. J. Syst. Bacteriol. 35: 292-295.
54. Wafa Al-Nassir (2011). Brucellosis Treatment & Management, http://emedicine.medscape.com/article/213430-treatment
55. Xie Xin. (1986). Orally administrable brucellosis vaccine: Brucella suis strain 2 vaccine. Vaccine. 4: 212-216.
Published
2014-06-01
How to Cite
Ghodasara, S., Savsani, H., Kalaria, V., & Bhadaniya, A. (2014). Manifestations of Brucellosis: A Systematic Review. The Indian Journal of Veterinary Science, 2(2), 1-13. Retrieved from http://ijvs.info/index.php/ijvs/article/view/33
Section
Articles